Antiasthmatic Activity of Hemidesmus Indicus Roots

Authors

  • Baheti Jagdish R.   Kamla Nehru College of Pharmacy Butibori Nagpur, Maharashtra, India

Keywords:

Hemidesmus indicus, Methanolic extract, Asthma.

Abstract

The present investigation was aimed to investigate the possible anti-asthmatic activity of methanolic extract of roots of Hemidesmus indicus(MEHI). Hemidesmus indicus extract is evaluated for its anti-asthmatic activity in Guinea pig ileum, tracheal chain and rat ileum preparation, compound 48/80 induced mast cell degranulation. Extract exhibited a significant (P<0.05, P<0.01) anti-asthmatic activity with the doses of 100, 200 and 300 mg/kg b.w. in rats and significant (P<0.05, P<0.01) inhibition in histamine and acetylcholine induced contraction of smooth muscle preparations. From results of this study we concluded that methanolic extract of Hemidesmus indicus roots has potential anti-asthmatic activity in various animal models and suggestive potential in prophylaxis and management of asthma.

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International Journal of Scientific Research in Science and Technology

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Published

2017-12-31

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Volume 3, Issue 8, November-December-2017

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Research Articles

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How to Cite

[1]
Baheti Jagdish R. "Antiasthmatic Activity of Hemidesmus Indicus Roots" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 3, Issue 8, pp.2006-2012, November-December-2017.