One-Pot Green Method for the Synthesis of Oxazine Derivatives Under Aqueous Medium

Authors

  • Santosh R. Kshirsagar  Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India
  • Ashok S. Pise  Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India
  • Sagar I. Shinde  Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India
  • Sandip P. Gondake  Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India
  • Valmik S. Kapase  Department of Chemistry, Dada Patil Mahavidyalaya, Karjat, Ahmednagar, Maharashtra, India

DOI:

https://doi.org/10.32628/IJSRST207482

Keywords:

1, 3-oxazine derivatives, One-pot multicomponent condensation, Polyphosphoric acid, Aqueous medium, Green method.

Abstract

A simple, convenient, and environmentally friendly method for the synthesis of 1,3-oxazine derivatives has been developed under aqueous conditions. The reaction proceeds via one pot multicomponent condensation of ? or ?- naphthol, aromatic aniline and formaldehyde using polyphosphoric acid as green catalyst. The current protocols are simple, requires less reaction time and provides high yields. Non-polluting synthetic procedures are used to avoid harmful effects of organic solvents on the environment.

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International Journal of Scientific Research in Science and Technology

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Published

2020-08-30

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Volume 7, Issue 4, July-August-2020

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Research Articles

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[1]
Santosh R. Kshirsagar, Ashok S. Pise, Sagar I. Shinde, Sandip P. Gondake, Valmik S. Kapase "One-Pot Green Method for the Synthesis of Oxazine Derivatives Under Aqueous Medium" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 7, Issue 4, pp.332-339, July-August-2020. Available at doi : https://doi.org/10.32628/IJSRST207482