Synthesis, Characterization and Biological Active 2 (Dimethylamino) Cyclohexane-1, 3-Dione

Authors

  • Veerappan Jeyachandran  Department of Chemistry, Bharath Institute of Higher Education and Research, Selaiyur, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.32628/IJSRST207667

Keywords:

Pyrazoles, Dimethylamino, Cyclohexane and Alkaloids.

Abstract

In the present work, the precursors 2- ( ( dimethylamino ) methylene ) cyclohexane-1,3-dione 4 and 2- ( ( dimethylamino ) methylene ) -5, 5-dimethylcyclohexane-1,3-dione 5 were synthesized from the reaction of 1,3-cyclohexanedione 1 or 5,5-dimethyl-1,3-cyclohexandione 2 with DMF-DMA 3, respectively following literature procedure (Scheme 1).

References

  1. Eicher, T.; Hauptmann, S. Edition IInd, Wiley-VCH, 2003, ISBN 3527307206.
  2. Nimbalkar, S.; Hote, S. V. Int. J. Rec. Innovation Trends in Comp. Comm., 2015, 3, 61.
  3. Amr, A. G.; Abdel-Latif, N. A.; Abdlla, M. M. Acta Pharm., 2006, 56, 1203.
  4. Chimichi, S.; Boccalini, M.; Hassan, M.M.M.; Viola, G.; Acqua, F. D.; Curini, M. Tetrahedron,2006, 62, 90.
  5. Kobayashi, Hisafumi, Kato, Motto; Nitani, Fumio, Chem. Abstr., 1989, 106 297008/g.
  6. Henry, T.A.; The Plant Alkoloids, Anmol Publicaion Pvt. Ltd., 1999.
  7. Dzvinchuk. I. B.; Tolmachova. N. A.; Chernega. A. N.; Lozinskii. M. O. Chem. Heterocycl. Compd., 2009, 45, 194.
  8. Toche, R. B.; Bhavsar, R. B.; Kazi, M. A.; Bagul, S. M.; Jachak, M. N. J. Heterocycl. Chem., 2010, 47, 287
  9. Liqiang, Wu.; Yang, L.; Yan, F.; Yang, C.; Fang, L. Bull. Korean Chem. Soc., 2010, 31, 1051.
  10. Liqiang, Wu.; Suying, Ma.; Yan, F.; Yang, C. Monatsh. Chem., 2010, 141, 565.
  11. Jiang, B.;Zhang, G.;Ning, Ma.;Shi, F.;Tu, S. J.;Kaur,P.; Li, G. Org. Biomol. Chem.,2011, 9, 3834.

International Journal of Scientific Research in Science and Technology

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Published

2021-01-30

Issue

Volume 8, Issue 1, January-February-2021

Section

Research Articles

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How to Cite

[1]
Veerappan Jeyachandran "Synthesis, Characterization and Biological Active 2 (Dimethylamino) Cyclohexane-1, 3-Dione" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 8, Issue 1, pp.07-09, January-February-2021. Available at doi : https://doi.org/10.32628/IJSRST207667