Effect of Different Solvents on Biginelli Reaction Using Layered Double Hyroxide (LDH) As an Ecofriendly Catalyst

Authors

  • N. S. Ghotkar  Dr. Sau. Kamaltai Gawai Institute of Engineering and Technology, Darapur, Dist. Amravati. Maharashtra. India
  • D. A. Pund  Shri R. R. Lahoti Science College Morshi. Amravati. Maharashtra. India
  • B. N. Berad   Shri Shivaji Science College Amravati, Maharashtra. India

DOI:

https://doi.org/10.32628/IJSRST218128

Keywords:

Biginelli reaction, one-pot procedure, 3,4-dihydropyrimidin-2(1H)- ones, LDH.

Abstract

A simple and efficient method of the 3,4- dihydropyrimidin-2(1H)-ones/thiones synthesis in good to high yield is described. It consists in a one-pot three-component Biginelli condensation using Layered double hydroxide (LDH) as catalyst. The effect of different solvents on the yields of final product also been studied. Highly polar solvent as well as highly non-polar gives less yields in presence of LDH catalyst.

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International Journal of Scientific Research in Science and Technology

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Published

2021-02-28

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Volume 8, Issue 1, January-February-2021

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Research Articles

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[1]
N. S. Ghotkar, D. A. Pund, B. N. Berad "Effect of Different Solvents on Biginelli Reaction Using Layered Double Hyroxide (LDH) As an Ecofriendly Catalyst" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 8, Issue 1, pp.223-226, January-February-2021. Available at doi : https://doi.org/10.32628/IJSRST218128