Synthesis of Chlorinated 3,5 Diaryl 2 Pyrazrolines

Authors

  • Pratiksha S. Rathod  Department of Chemistry, Kohinoor Arts, Commerce and Science College, Khultabad, Maharashtra, India
  • Shilpa G. Chavan  Department of Botany, Dr Babasaheb Ambedkar Marathwada University, Aurangabad, Maharashtra, India

DOI:

https://doi.org/10.32628/IJSRST218579

Keywords:

Pyrazolines, heterocyclic, chlorinated 3,5-diary-l-2-pyrazolines, chloro chalcones, IR, 1H-NMR

Abstract

Pyrazolines are important nitrogen containing 5-membered heterocyclic compounds. Various, pyrazoline derivatives have been found to possess considerable biological and pharmaceutical applications as activities, which stimulated the research activity in this field. The chlorinated 3,5-diary-l-2-pyrazolines has been synthesized by reaction of appropriately substituted chloro chalcones and mono-substituted hydrazine’s have been synthesized. These compounds were characterized using IR, 1H-NMR and Mass spectra and Elemental analysis. They possess some potent biological activities. Therefore, biological screening of novel compounds has been also done.

References

  1. Joshi. M.G.;Wadodkar,K.N. Indian J,Chem.1981,20B,1090.
  2. Sharma, T.C.;Pawar,S.R.;Ready, N.J Acta chim.Hung. 1983,112,159.
  3. Dhar,D.N.; Raghunathan, R.Indian J.Chem.1984,23B,1187.
  4. Levai,A.J. Heterocycl. chem.2002,39,1.
  5. Ried,W.;Dankert, G.Chem.Ber.1957,90,2707.
  6. Levai,A.J. Heterocycl. chem.1998,35,13.
  7. Levai,A.J. Heterocycl. chem.2003,9,287.
  8. Dawey,W.;gwilt,J.R.J Chem.soc.1957,1008.
  9. Jha,B.C.Amin,G.C. Tetrahedron 1958,2,241.

International Journal of Scientific Research in Science and Technology

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Published

2021-10-30

Issue

Volume 8, Issue 5, September-October-2021

Section

Research Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Pratiksha S. Rathod, Shilpa G. Chavan "Synthesis of Chlorinated 3,5 Diaryl 2 Pyrazrolines" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 8, Issue 5, pp.476-479, September-October-2021. Available at doi : https://doi.org/10.32628/IJSRST218579