Studies On Novel Oxadiazole Compounds and their Metal Complex

Authors

  • Rajesh Kumar A. Chauhan   Sheth L. H. Science College, Mansa, Gujarat, India
  • Kaushik Joshi  D K V Arts & Science College, Jamnagar, Gujarat, India
  • Vipul Joshi  D K V Arts & Science College, Jamnagar, Gujarat, India
  • Ninad Bhatt  D K V Arts & Science College, Jamnagar, Gujarat, India
  • Dr. G. D. Acharya  R. R. Mehta Science College, Palanpur, Gujarat, India

Keywords:

5-((4-bromophenoxy)methyl)-3-(((8-hydroxyquinolin-5-yl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione, Spectroscopies study, Magnetic moment, Antifungal properties

Abstract

Mannich reaction between 5-amino-8-quinolinol (AMQ) and 5-(4-bromo phenoxy methyl acetyl)-1,3,4-oxadiazole-2(3H)-thione (POD) in the presence of formaldehyde was gave 5-((4-bromophenoxy)methyl)-3-(((8-hydroxyquinolin-5-yl)amino)methyl)-1,3,4-oxadiazole-2(3H)-thione (BODMHQ), which was characterized by elemental analysis and spectral studies. The transition metal chelates viz. Cu2+, Ni2+ , Co2+ , Mn2+ and Zn2+ of the product were prepared and characterized by metal-ligand (M:L) ratio, IR and reflectance spectroscopies and magnetic properties. The antifungal activity of that synthesized compound and its metal chelates was screened against various fungi. The results show that all these samples are good antifungal agents.

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International Journal of Scientific Research in Science and Technology

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Published

2018-12-30

Issue

Volume 4, Issue 11, November-December-2018

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Research Articles

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How to Cite

[1]
Rajesh Kumar A. Chauhan , Kaushik Joshi, Vipul Joshi, Ninad Bhatt, Dr. G. D. Acharya, " Studies On Novel Oxadiazole Compounds and their Metal Complex, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 11, pp.715-720, November-December-2018.