Green Synthesis, Characterisation and Antibacterial activities of 4-Nitroacetophenonethiosemicarbazone and 3-Nitrobenzaldehyde thiosemicarbazone

Authors

  • Kamal Kishor Verma  Department of Chemistry, Seth RL Saharia Government PG college Kaladera, Jaipur, Rajasthan, India
  • Narendra Nirwan  Department of Chemistry, SPC Government College Ajmer, Rajasthan, India

Keywords:

Thiosemicarbazone, Microwave Irradiations, Antibacterial Activity.

Abstract

The present study describes the Synthesis, characterization and biological activities of two thiosemicarbazone ligands i.e. 4-Nitroacetophenonethiosemicarbazone (4NAT) and 3-Nitrobenzaldehyde thiosemicarbazone (3NBT). The thiosemicarbazone ligands i.e. 4NAT and 3NBT have been synthesized by the condensation reaction of 4-Nitroacetophenone and 3-Nitrobenzaldehyde with thiosemicarbazide by conventional heating method as well as microwave irradiations method. The synthesized compounds have been characterized by elemental analysis, melting point determination, FTIR, UV-visible spectral analysis. The synthesized ligands have been screened in vitro for antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis bacteria.

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International Journal of Scientific Research in Science and Technology

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Published

2022-08-30

Issue

Volume 9, Issue 4, July-August-2022

Section

Research Articles

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How to Cite

[1]
Kamal Kishor Verma, Narendra Nirwan "Green Synthesis, Characterisation and Antibacterial activities of 4-Nitroacetophenonethiosemicarbazone and 3-Nitrobenzaldehyde thiosemicarbazone" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 9, Issue 4, pp.685-689, July-August-2022.