In silico ADME, Bioactivity and Toxicity Prediction of some Selected Antiviral Drugs.

Authors

  • Munagala Alivelu  Department of Chemistry, Pingle Govt. College for Women(A), Warangal, Telangana, India
  • Natte Kavitha  Department of Botany, MKR Govt. Degree College, Devarakonda. Nalgonda, Telanagana, India
  • Cherkupally Ramaraju  

DOI:

https://doi.org//10.32628/IJSRST2296101

Keywords:

Insilco, Antiviral, Drug likeness, ADME, COVID-19.

Abstract

Viruses have been the cause of some of the world's worst and most dreadful diseases. COVID-19 is one of them, and it is the name given to the novel corona virus discovered in 2019. Due to the unavailability of any proven treatment, there is an urgent need for therapeutics for COVID-19. In this computational investigation, ADME profiles and bioactivity results of 2-deoxy D-glucose (1), Hydroxy chloroquine (2), and Favipiravir (3) compounds were calculated. Drug likeness criteria based on Lipinski and Veber’s rules indicate that the compounds have classic physicochemical and pharmacokinetic properties that make them a good candidate for oral drug administration.

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International Journal of Scientific Research in Science and Technology

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Published

2022-12-30

Issue

Volume 9, Issue 6, November-December-2022

Section

Research Articles

License

Copyright (c) IJSRST

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

[1]
Munagala Alivelu, Natte Kavitha, Cherkupally Ramaraju, " In silico ADME, Bioactivity and Toxicity Prediction of some Selected Antiviral Drugs., International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 9, Issue 6, pp.637-643, November-December-2022. Available at doi : https://doi.org/10.32628/IJSRST2296101