Study of antimicrobial and antifungal activities of some synthesized 2-(2-amino-1, 3-Oxazol-4-yl)-4-substitutednaphthalen-1-ol

Authors

  • Dasharath M. Chavhana  Department of Chemistry, Indira Mahavidyalaya, Kalamb, Yavatmal, Maharashtra, India
  • Shrikant S. Patil  Professor and Director, Department of lifelong learning and Extension, Sant Gadge Baba Amravati University, Amravati, Maharashtra, India

Keywords:

Antimicrobial, antifungal, microbes, agar well diffusion assasy method.

Abstract

New oxazole derivative of substitutednaphthol were ecofriendly and efficiently be synthesized like 2-(2-amino-1, 3-oxazol-4-yl)-4-substitutednaphthalen-1-ol by cyclization of 1-[2-(4-Substituted-1-hydroxynaphthalen-2-yl)-2-oxoethyl]thiocarbamide by utilizing elemental sulphur as a chief, easily available, non toxic catalyst. Some of these compounds were screen for their antimicrobial and antifungal activity against some selected microbe like C. albicans, A. niger, S. Typhi, E. coli, S. dysenteriae, K. pneumoniae, S. aureus by agar well diffusion assay method carried out. The compounds screen against selected microbe shows good results.

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International Journal of Scientific Research in Science and Technology

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Published

2018-01-30

Issue

Volume 4, Issue 1, January-February-2018

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Research Articles

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How to Cite

[1]
Dasharath M. Chavhana, Shrikant S. Patil, " Study of antimicrobial and antifungal activities of some synthesized 2-(2-amino-1, 3-Oxazol-4-yl)-4-substitutednaphthalen-1-ol, International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011, Volume 4, Issue 1, pp.66-73 , January-February-2018.