Recent Developments in the Synthetic Chemistry of Pyrimido [4, 5-d] pyrimidine Derivatives: A Systematic Review
Keywords:
Pyrimido [4, 5-d] pyrimidine, Heterocyclic compound, Pharmacological activities, Synthesis.Abstract
This review focuses on the recent development of synthesis of pyrimido [4, 5-d] pyrimidine derivatives. Pyrimido [4, 5-d] pyrimidine derivatives are important heterocyclic compound which possess diverse pharmacological activities such as anticancer, antitumor, antioxidant, antiviral, antibacterial anti-allergic and anti-inflammatory activities. Therefore, organic chemists are interested in the synthesis of these bioactive heterocycles. In this review, we have compile the recent literature report of various synthetic procedures for synthesis of pyrimido [4, 5-d] pyrimidine derivatives.
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