Synthesis and Biological Activity of Sulphadiazine Schiff Bases of Isatin and their N-Mannich bases
Keywords:
Antimicrobial activity , Sulphadiazine Schiff Bases.Abstract
Sulphadiazinyl Schiff bases of isatin and derivatives and their Mannich bases were synthesized. Their chemical structure have been confirmed by IR, 1HNMR and elemental analysis. Antimicrobial evaluation were done against pathogenic bacteria and fungi. Nearly all the synthesized compounds exhibited antimicrobial activity against gram positive and gram negative bacteria at 500 μg concentration.
References
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- Singh R, Sharma S, Banarasi B. Synthesis, Characterization And Evaluation of 2-Imino Benzothiazole Derivatives As Anticonvulsant Agents. International Journal of Pharmaceutical Sciences and Research. 2021; 5(5):213-217.
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2024-02-29
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[1]
Mukesh, Dr. Girija Shankar Tripathi "Synthesis and Biological Activity of Sulphadiazine Schiff Bases of Isatin and their N-Mannich bases" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 11, Issue 1, pp.615-620, January-February-2024.