Synthesis ,characterization and Pharmacological activities of 7-substituted Imino-phenothiazine-2-methyl-4-Quinolones

Authors

  • Tasneem K. H. Khan  Chemistry , Rtmnu, ACET , Nagpur, Maharashtra, India
  • M.N. Narule  Chemistry, Rtmnu, VVACSC, Samudrapur , Maharashtra, India
  • M. D. Choudhari  Chemistry , Rtmnu, BDCOE , Wardha, Maharashtra, India

Keywords:

Heterocyclic, Quinolones, phenothiazines

Abstract

The pharmacological activities related to phenothiazine, with an account on the synthesis of 7-substituted imino-phenothiazine- 2-methyl-4-quinolones 1 (Scheme 1) and their related compounds. The structure of the synthesized compound was predicted by elemental analysis, IR spectroscopy, 1H NMR, C13 NMR and Mass spectra, successfully confirming the prepared derivatives

References

  1. J. W. Britton; cornell vet., 31, 1941, 1-12; Chem. Abstr., 35, 1941, 75408.
  2. C. E. Howell and J. W. Britton Cernell vet., 32, 1942, 225-65; Chem. Abstr., 36, 1942,62402.
  3. L. E. Swanson J. Am. Vet. Med. Assoc., 105, 1944, 134-5; Chem. Abstr., 38, 1944,59578.
  4. P. D. Hardwood and D. I. Stunz; Proc. Helm in. Thol. Soc., 12, 1945, 1-2; Chem. Abstr.,40, 1946, 15875.
  5. R. Deschiens and L. Lamy; Compt. Abstr. soc. biol. 139, 1945, 44-9; Chem. Abstr., 40,1946, 44344.
  6. Bennett, G. Dwight; Am. J. Vet. Res, 29(12), 1968, 2325-30; Chem. Abstr., 70, 1969,459428v.
  7. D. D. William; Chem. Abstr., 70 1969, 14419a.
  8. A. O. Foster, F. D. Enzie and D. E. Thompson; Chem. Abstr., 54, 1960, 92304h.
  9. Y. Ueno, Y. Takeuchi, J. Koshitani and T. Yoshida; J. Hetro Chem., 18, 1981, 645-647.
  10. T. Zsolnai and I. Stanchich; Magyar Kem. Lapja, 4, 1949, 235; Chem. Abstr., 43, 1949,8434h.
  11. M. Tomita and W. Watanabe J. Pharm. soc. Japan, 71, 1951, 1198-1203; Chem. Abstr.,46, 1952, 7618c.
  12. J. Bernstein, H. L. Yale and H. A. Losee; Chem. Abstr., 70, 1969, 77984b.
  13. G. E. Martin, J. D. Korp, J. C. Turley and I. Bernal; J. Hetero Chem., 15, 1978, 721- 29.
  14. C. Corral, J. Lissaretzky and G. Quintanilla; J. Hetero. Chem 15, 1978, 969-75.
  15. F. DeEds and J. O. Thomas Nalt. med., 114, 1950, 632 ;Chem. Abstr., 45, 1951, 3942.
  16. F. DeFds and A. B. Stockton and J. O. Thomas J. Pharmacol. Exptl. therap.,64, 1938, 280; Chem. Abstr., 33, 1939, 4673.
  17. M. Lipson J. Expti. Bio. Med. Sci., 18, 1940, 269-72; Chem. Abstr., 35, 1941, 15115.

International Journal of Scientific Research in Science and Technology

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Published

2018-01-30

Issue

Volume 4, Issue 3, January-February-2018

Section

Research Articles

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How to Cite

[1]
Tasneem K. H. Khan, M.N. Narule, M. D. Choudhari "Synthesis ,characterization and Pharmacological activities of 7-substituted Imino-phenothiazine-2-methyl-4-Quinolones" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 4, Issue 3, pp.203-206, January-February-2018.