Microwave Assisted Synthesis, Spectral and Antibacterial Studies of Complex of 2-Hydroxy-6-methylnicotinic acid with Mn(II)

Authors

  • S. K. Verma  GCRC, P. G. Department of Chemistry, Govt. Dungar College (NAAC ‘A’ Grade), MGS University, Bikaner, Rajasthan, India
  • N. Bhojak  GCRC, P. G. Department of Chemistry, Govt. Dungar College (NAAC ‘A’ Grade), MGS University, Bikaner, Rajasthan, India

Keywords:

2-Hydroxy-6-methylnicotinic acid, microwave irradiation, antibacterial studies.

Abstract

New transition metal complex of 2-hydroxy-6-methylnicotinic acid (H26MnicO) Na2[Mn(H6MnicO)2Cl2] has been prepared by microwave irradiation method. 2-Hydroxy-6-methylnicotinate coordinates through O,O-chelation to the transition metal(II) ion to form octahedral complex as shown by FT-IR and UV-Visible spectral analysis. The ligand and its complex have been screened in-vitro for antibacterial

References

  1. F. Depeint, W. R. Bruce, N. Shangari, R. Mehta and P. J. O'Brien, Chem Biol Interact, 163 (2006) 94.
  2. B. G. Brown and X. Q. Zhao, Am J Cardiol, 101 (2008) B58-B62.
  3. T. Suksrichavalit, S. Prachayasittikul, C. Nantasenamat, C. I. N. Ayudhya, and V. Prachayasittikul, European Journal of Medicinal Chemistry, 44 (2009) 3259.
  4. D. Wang, X. Cheng, Y. Shi, E. Sun, X. Tang, C. Zhuang and T. Shi, Solid State Sci, 11 (2009) 195-199.
  5. R. Singh, R. S. S. Rao, J Mol Struct, 71 (1981) 23-30.
  6. A. G. Gilman, L. S. Goodman, and A. Gilman, The pharmacological basis of therapeutics, 6th ed., (1980) Macmillan, New York.
  7. A. R. Victoria and D. W. Michael, Chem. Mater. Rev., 137 (1994) 357- 401.
  8. A. M. Beatty, Coord. Chem. Rev., 246 (2003) 131-143.
  9. A. J. Boulton and A. Mckillop, Comprehensive Heterocyclic Chemistry: The Structure, Reactions, Synthesis and Uses of Heterocyclic Compounds, Vol. 2, (1984) Pergamon, Oxford.
  10. C. Y. Sun, X. J. Zheng and L. P. Jin, Zeitschrift Fur Anorganische und Allgemeine Chemie., 630 (2004) 1342-1347.
  11. S. K. Verma and N. Bhojak, World Journal of Pharmacy and Pharmaceutical Sciences, 6(6) (2017) 490-514.
  12. Dogra S K, J. Mol. Struct., 737 (2005) 189-199.
  13. C. L. Ma, Q. L. Li and R. F. Zhang, Inorg Chim Acta, 362 (2009) 2937-2940.
  14. H. H. Zou, S. H. Zhang, Y. Xiao, C. Feng and Y. G. Wang, Struct Chem, 22 (2011) 135-140.
  15. S. M. O. Quintal, H. I. S. Nogueira, V. Felix and M. G. B. Drew, Polyhedron, 2 (2002) 2783-2791.
  16. Y. M. Li, Y. X. Che and J. M. Zheng, Chinese J. Struct. Chem., 5 (2006) 572-576.
  17. S. M. O. Quintal, H. I. S. Nogueira, V. Felix and M. G. B. Drew, Dalton Transactions, 7 (2002) 4479-4487.
  18. N. Yadav and N. Bhojak, The Int.J.Eng.Sci., 2(2) (2013) 166-168.
  19. Y. F. Yue, W. Sun, E. Q. Gao, C. J. Fang, S. Xu and C. H. Yan, Inorganica Chimica Acta, 360 (2007) 1466-1473.
  20. D. A. Kose, H. Icbudak and H. Necefoglu, Hecettepe J. Biol. & Chem., 35(2) (2007) 123-128.
  21. W. Lewandowaski, B. Desiewicz, P. Koczon, J. Skierski, K. D. Teperek, R. Swislocka, L. Fuks, W. Priebe and A. P. Mazurek, Journal of Molecular Structure, 604 (2002) 189-193.
  22. J. Miklovic, P. Sega, D. Miklos, J. Titis, R. Herchel and M. Melník, Chemical Papers, 62(5) (2008) 464-471.
  23. P. C. R. Soares-Santos, H. I. S. Nogueira, J. Rocha, V. Felix, M. G. B. Drew, R. A. S. Ferreira, L. D. Carlos and T. Trindade, Polyhedron, 22 (2003) 3529-3539.
  24. V. B. Di-Marco, A. Tapparo, A. Dolmella and G. G. Bombi, Inorganica Chimica Acta, 357 (2004) 135-142.
  25. K. Nakamoto, Infrared and Raman spectra of inorganic and coordination compounds, Part B (5th. Ed.), (1963) New York, Willey.
  26. C. F. Edward, W. P. Griffith, A. J. P. White and D. J. Williams, J. Chem. Soc., Dalton Trans., 12 (1993) 3813.
  27. M. S. Saleh, J. Indian Chem. Soc., 70 (1993) 202.
  28. K. A. Idriss, M. S. Saleh and H. Sedaira, Monat. Chem., 122 (1991) 507.
  29. Raja Ram, K. K. Verma, H. S. Bhandari, and N. Bhojak, IARJSET, 2(11) (2015) 40-43.
  30. S. F. A. Kettle, Physical Inorganic Chemistry, (1996) Springer-Verlag Berlin-Heidelberg.
  31. B. N. Figgis and M. A. Hitchman, Ligand Field Theory and Its Applications, (2000) Willey-VCH, New York.
  32. K. F. Purcell and J. C. Kotz, Inorganic Chemistry, (1977) W. B. Saunders, Philadelphia.
  33. R. N. Prasad, M. Jindal and M. Jain, J Indian Chem Soc., 9 (1984) 1-3.
  34. K. K. Verma, Raja Ram, K. Sharma and N. Bhojak, World Journal of Pharmacy and Pharmaceutical Sciences, 5(4) (2016) 1307-1318.
  35. J. Lewis and R. Wilkins, Modern Coordination Chemistry, Interscience, (1960) New York.

International Journal of Scientific Research in Science and Technology

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Published

2018-02-28

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Volume 4, Issue 2, January-February-2018

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Research Articles

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[1]
S. K. Verma, N. Bhojak "Microwave Assisted Synthesis, Spectral and Antibacterial Studies of Complex of 2-Hydroxy-6-methylnicotinic acid with Mn(II)" International Journal of Scientific Research in Science and Technology(IJSRST), Online ISSN : 2395-602X, Print ISSN : 2395-6011,Volume 4, Issue 2, pp.512-517, January-February-2018.