Ultrasonic Mediated Synthesis of Dihydropyrano [2, 3-C] Pyrazole Derivatives Catalyzed By Cyanuric Acid/1-Methyl Imidazole
DOI:
https://doi.org/10.32628/IJSRST24114100Keywords:
Multicomponent synthesis, pyranopyrazoles, Ultrasound irradiationAbstract
A Novel approach for the synthesis of dihydropyrano[2,3-c] pyrazoles via four-component reaction of ethyl acetoacetate, hydrazine hydrate, aromatic aldehydes and malononitrile at room temperature under ultrasound irradiation is described. The reaction has been catalyzed by cyanuric acid and 1-methyl inidazole in aqueous medium. This protocol afforded several advantages such as easily available catalyst, simple operational procedure, excellent yield and ultrasound irradiation.
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