Phytochemical Screening and Pharmacological Study of Aegle Marmelos : A Review

Shalini Shukla; S. Ramasamy; Neetika Misra

doi:10.32628/IJSRST24114126

Authors

Shalini Shukla Department of Pharmacy, MJP Rohilkhand University, Bareilly, Uttar Pradesh, India Author
S. Ramasamy Department of Pharmacy, MJP Rohilkhand University, Bareilly, Uttar Pradesh, India Author
Neetika Misra Department of Pharmacy, MJP Rohilkhand University, Bareilly, Uttar Pradesh, India Author

DOI:

https://doi.org/10.32628/IJSRST24114126

Keywords:

Aegle Marmelos, Phytochemical, Pharmacological Activity, Traditional use

Abstract

Aegle marmelos, commonly called "Bael," is a native Indian herb. The Bael tree—also referred to as the golden apple or Bengal quince—belongs to the Rutaceae family of medium-sized deciduous trees. Traditional medicine has traditionally utilized all portions of the sapling, including the fruit, woof, roots, leaves, and stems because they all have medicinal properties. Regardless of how old the fruit is, this is accurate. The composition of Aegle marmelos has been found to include flavonoids, fatty acids, carbohydrates, tannins, alkaloids, terpenoids, vitamins, and essential oils, among other things. The plant has pharmacological properties that can modulate the immune system, relieve pain, reduce inflammation, treat arthritis, lower blood cholesterol, fight cancer, fight viruses, treat ulcers, and promote wound healing. Its other properties include anti-proliferative, hepatoprotective, antidiabetic, antibacterial, and antifungal properties. Therefore, those who are keen to carry out further research on.

Downloads

Download data is not yet available.

References

Rupeshkumar M, Kavitha K, Haldar PK. Role of herbal plants in the diabetes mellitus therapy: An overview. Int J Appl Pharm. 2014;6(3):1-3.

Kaur A, Kalia M. Physico chemical analysis of bael (Aegle marmelos) fruit pulp, seed and pericarp. Chemical Science Review and Letters. 2017;6(22):1213-8

Badam L, Bedekar SS, Sonawane KB, Joshi SP. In vitro antiviral activity of Bael (Aegle marmelos Corr.) upon human Cox sacki viruses B1-B6. J. Commun Dis. 2002; 34: 88.

Gupta AK, Tandon N. Review on Indian medicinal plants. Indian council of medicinal research, New Delhi. 2004; 312.

M. Shoeb, Bangladesh J. Pharmacol., 2006, 1, 35-41.

G. Kumar, L. Karthik, K.V.B. Rao, International Journal of Pharmaceutical Sciences and Research, 2010, 1, 60-67.

G. Kumar, L. Karthik, K.V.B. Rao, International Journal of Pharmaceutical Sciences Review and Research, 2010, 4, 141-144.

G. Kumar, L. Karthik, K.V.B. Rao, Pharmacologyonline, 2010, 3, 155-163.

G. Kumar, L. Karthik, K.V.B. Rao, Journal of Pharmacy Research, 2010, 3, 539-542.

R. Vadivelan, P. Umasankar, M. Dipanjan, S.P. Dhanabal, A. Shanish, M.N. Satishkumar, K. Elanko, Der Pharmacia Sinica, 2011, 2, 299-304.

C.L. Priya, G. Kumar, L. Karthik, K.V.B. Rao, Pharmacologyonline, 2010, 2, 228-237.

P.M. Gaikwad, S. Vidyadhara, V.V. Nimbalkar, Der Pharmacia Sinica, 2011, 2, 155-160.

S. Kalita, G. Kumar, L. Karthik, K.V.B. Rao, Pharmacologyonline, 2011, 1, 59-67.

A.A. Rahuman, G. Gopalakrishnan, P. Venkatesan, K. Geetha, Parasitol. Res., 2008, 102, 867-873. [12] S. Lakheda, R. Devalia, U.K. Jain, N. Gupta, A.S. Raghuwansi, N. Patidar, Der Pharmacia Sinica, 2011, 2, 127-130. DOI: https://doi.org/10.1007/s00436-007-0839-6

Pathirana CK, Madhujith T, Eeswara J. Bael (Aegle marmelos L. Corrêa), a medicinal tree with immense economic potential. Advances in Agriculture. 2020 Dec 9;2020. DOI: https://doi.org/10.1155/2020/8814018

Uppugalla S, Srinivasan P. High-performance supercapacitor coin cell: polyaniline and nitrogen, sulfur-doped activated carbon electrodes in aqueous electrolyte. Journal of Solid State Electrochemistry. 2019 Jan;23(1):295- 306. DOI: https://doi.org/10.1007/s10008-018-4128-3

Uppugalla S, Male U, Srinivasan P. Design and synthesis of heteroatoms doped carbon/polyaniline hybrid material for high-performance electrode in supercapacitor application. ElectrochimicaActa. 2014 Nov 10;146:242-8. DOI: https://doi.org/10.1016/j.electacta.2014.09.047

Mulyaningsih AP, Yetti RD, Rivai H. Phytochemical and pharmacological review of Maja (Aegle marmelos). World J. Pharm. Pharm. Sci. 2020 Jun 27;9:19-42.

Wali A, Gupta M, Mallick SA, Guleria S, sharma M. Antioxidant Potential and Phenol Profile of Bael Leaf (Aegle marmelos). Indian J Agric Biochem. 2015; 28(2): 138-142. DOI: https://doi.org/10.5958/0974-4479.2015.00007.6

P.V. Joshi, R.H. Patil, V.L. Maheshwari, Natural Product Radiance, 2009, 8, 498-502. [34] S. Brijesh, P. Daswani, P. Tetali, N. Antia, T. Birdi, BMC Complement Altern. Med., 2009, 9, 47.

Kaur A, Kalia M. Physico chemical analysis of bael (Aegle marmelos) fruit pulp, seed and pericarp. Chemical Science Review and Letters. 2017;6(22):1213-8.

Singh SK. Aegle marmelos protects hepatocytes from Paracetamol induced hepatotoxicity. Indian J.Sci.Res. 2013; 4(1): 53-56.

Sabu MC, Kuttan R. Antidiabetic activity of Aegle marmelos and its relationship with its antioxidant properties. Indian Journal of physiology and pharmacology. 2004 Jan 1;48(1):81-8.

Male U, Uppugalla S, Srinivasan P. Effect of reduced graphene oxide–silica composite in polyaniline: electrode material for highperformance supercapacitor. Journal of Solid State Electrochemistry. 2015 Nov;19(11):3381-8. DOI: https://doi.org/10.1007/s10008-015-2978-5

George M, Joseph L, Sreelakshmi R. Phytochemical and pharmacological screening of in vivo antiinflammatory activity of Aegle marmelos (L.) Corr. Serr. Journal of Chemical and Pharmaceutical Research. 2016; 8(2): 330-334.

Ghangale GR, Surve VS, Anbarasan K, Gatne MM. Evaluation of Aegle marmelos (Bael) for antiinflammatory activity in rats. The Journal of Bombay Veterinary College. 2008; 16(1).

Rathee D, Kamboj A, Sidhu S. Augmentation of hepatoprotective potential of Aegle marmelos in combination with piperine in carbon tetrachloride model in wistar rats. Chemistry Central Journal. 2018 Dec;12(1):1-3 DOI: https://doi.org/10.1186/s13065-018-0463-9

Sachin Kumar, Ramesh B. Bodla, Himangini Bansal. Antioxidant Activity of Leaf Extract of Aegle marmelos Correa ex Roxb. Pharmacognosy Journal. 2016; 8(5):447-450. DOI: https://doi.org/10.5530/pj.2016.5.6

Singh AP, Singh AP. Aegle marmelos (L.)(Bael): A Systematic Review. Journal of Drug Delivery and Therapeutics. 2021 Jun 15;11(3-S):131-6. DOI: https://doi.org/10.22270/jddt.v11i3-S.4834

Sekar DK, Kumar G, Karthik L, Rao KB. A review on pharmacological and phytochemical properties of Aegle marmelos (L.) Corr. Serr.(Rutaceae). Asian Journal of Plant Science and Research. 2011;1(2):8-17.

Panda S, Kar A. Evaluation of the antithyroid, antioxidative and antihyperglycemic activity of scopoletin from Aegle marmelos leaves in hyperthyroid rats. Phytotherapy Research: An International Journal Devoted to Pharmacological and Toxicological Evaluation.

Sekar DK, Kumar G, Karthik L, Rao KB. A review on pharmacological and phytochemical properties of Aegle marmelos (L.) Corr. Serr.(Rutaceae). Asian Journal of Plant Science and Research. 2011;1(2):8-17.

Uppugalla S, Male U, Srinivasan P. Design and synthesis of heteroatoms doped carbon/polyaniline hybrid material for high performance electrode in supercapacitor application. ElectrochimicaActa. 2014 Nov 10;146:242-8. DOI: https://doi.org/10.1016/j.electacta.2014.09.047

Vyas A, Bhargava S, Bhargava P, Shukla SS, Pandey R, Bhadauria RS. Evaluation of antipyretic potential of Aegle marmelos (L.) Correa leaves. Oriental Journal of Chemistry. 2011 Jan 1;27(1):253.

R. Sivaraj, A. Balakrishnan, M. Thenmozhi, R. Venckatesh, Journal of Pharmacy Research 2011, 4, 1507-1508.

C.C. Gavimath, Y.L. Ramachandra, S.P. Rai, H.V. Sudeep, P.S.S. Ganapathy, B.T. Kavitha, Asian Journal of Bio Science, 2008, 3, 333-336.

K.U. Rijamol, T. Thomas, C. Sadasivan, Int. Journal (Sciences), 2008, 2, 134-138.

C. Rajasekaran, E. Meignanam, N. Premkumar, T. Kalaivani, R. Siva, V. Vijayakumar, S. Ramya, R. Jayakumararaj, Ethnobotanical Leaflets, 2008, 12, 1124-1128.

P.V. Joshi, R.H. Patil, V.L. Maheshwari, Natural Product Radiance, 2009, 8, 498-502.

S. Brijesh, P. Daswani, P. Tetali, N. Antia, T. Birdi, BMC Complement Altern. Med., 2009, 9, 4. DOI: https://doi.org/10.1186/1472-6882-9-47

Sharma GN, Dubey SK, Sharma P, Sati N. Medicinal values of bael (Aegle marmelos)(L.) Corr.: A review. Int J Curr Pharm Rev Res. 2011;2(1):12-22.

A. Veerappan, S. Miyazaki, M. Kadarkaraisamy, D. Ranganathan, Phytomedicine, 2007, 14, 209-215. DOI: https://doi.org/10.1016/j.phymed.2006.05.004

Sekar DK, Kumar G, Karthik L, Rao KB. A review on pharmacological and phytochemical properties of Aegle marmelos (L.) Corr. Serr.(Rutaceae). Asian Journal of Plant Science and Research. 2011