Isolation and Extraction of as Ferulic Acid from Medicinally Active Andrographis Paniculata Plant and Synthesis of its Analogues
DOI:
https://doi.org/10.32628/IJSRST2512131Keywords:
Ferulic acid, antioxidant, isolation, extractionAbstract
Ferulic acid has been shown to have biological activities such as antimicrobial, antioxidant, anti-inflammatory, anti-thrombogenic and anticancer properties. Moreover, it decreases liver and serum cholesterol, increases sperm viability, and all of these advantages are advantageous for coronary heart disease. Apart from this, it exhibits great commercial potential in the food, health and cosmetic industries. Because ferulic acid is absorbed and metabolized by the human body, it has additional advantages. Thus, devised a plan to extract and isolate ferulic acid from Andrographis Paniculata based on the aforementioned features. Based on the properties of this, we have strategies to isolate the ferulic acid and synthesis of their analogues like ester and amide. Which were characterized by 1HNMR and GCMS.
Downloads
References
Mota, F. L., Queimada, A. J., Pinho, S. P., & Macedo, E. A. Industrial & Engineering Chemistry Research, 47(15), 5182-5189, (2008). DOI: https://doi.org/10.1021/ie071452o
de Oliveira, D. M., Finger‐Teixeira, A., Rodrigues Mota, T., Salvador, V. H., Moreira‐Vilar, F. C., Correa Molinari, H. B., & Dantas dos Santos, W. Plant biotechnology journal, 13(9), 1224-1232, (2015). DOI: https://doi.org/10.1111/pbi.12292
Zhao, Z., & Moghadasian, M. H. Food Chemistry, 109(4), 691-702, (2008). DOI: https://doi.org/10.1016/j.foodchem.2008.02.039
Kumar, N., & Pruthi, V. Biotechnology Reports, 4, 86-93, (2014). DOI: https://doi.org/10.1016/j.btre.2014.09.002
Bagchi, D., Moriyama, H., & Swaroop, A. Green coffee bean extract in human health. CRC Press, (2016). DOI: https://doi.org/10.1201/9781315371153
Gelinas, P., & McKinnon, C. M. International journal of food science & technology, 41(3), (2006). DOI: https://doi.org/10.1111/j.1365-2621.2005.01057.x
Beejmohun, V., Fliniaux, O., Grand, É., Lamblin, F., Bensaddek, L., Christen, P., & Mesnard, F. Phytochemical Analysis: An International Journal of Plant Chemical and Biochemical Techniques, 18(4), 275-282, (2007). DOI: https://doi.org/10.1002/pca.973
Quinde-Axtell, Z., & Baik, B. K., Journal of agricultural and food chemistry, 54(26), 9978-9984, (2006). DOI: https://doi.org/10.1021/jf060974w
Luthria, D. L., & Pastor-Corrales, M. A. P. Journal of food composition and analysis, 19(2-3), 205-211, (2006). DOI: https://doi.org/10.1016/j.jfca.2005.09.003
Anson, N. M., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. Journal of Cereal Science, 49(2), 296-300, (2009). DOI: https://doi.org/10.1016/j.jcs.2008.12.001
Buanafina, M. Mol. Plant, 2, 861–872, (2009). DOI: https://doi.org/10.1093/mp/ssp067
Dyk, J.S.V. and Pletschke, B.I. Biotechnol. Adv. 30,1458–1480, (2012). DOI: https://doi.org/10.1016/j.biotechadv.2012.03.002
Escobar, J., Lora, E., Venturini, O., Yanez, E., Castillo, E. and Almazan, O. Renew. Sustain. EnergyRev. 13, 1275–1287, (2009). DOI: https://doi.org/10.1016/j.rser.2008.08.014
Franke, R., Humphreys, J.M., Hemm, M.R., Denault, J.W., Ruegger, M.O., Cusumano, J.C. and Chapple, C. Plant J. 30, 33–45, (2002). DOI: https://doi.org/10.1046/j.1365-313X.2002.01266.x
Fry, S. Annu. Rev. Plant Physiol. 37, 165–186, (1986). DOI: https://doi.org/10.1146/annurev.pp.37.060186.001121
Downloads
Published
Issue
Section
License
Copyright (c) 2025 International Journal of Scientific Research in Science and Technology

This work is licensed under a Creative Commons Attribution 4.0 International License.
https://creativecommons.org/licenses/by/4.0