Complexation of Gadolinium Metal Ion with Medicinal Drugs in Mixed Solvent Media: Thermodynamic Aspect

Authors

  • Sandeep Sampal Department of Chemistry, Kalikadevi Arts, Commerce & Science College, Shirur (K) Dist-Beed, Maharashtra, India Author
  • Milind Gaikwad Department of Chemistry, Rajmata Jijau Mahavidyalaya, Kille Dharur, Maharashtra, India Author
  • Uddhav Chaudhar Department of Chemistry, Kalikadevi Arts, Commerce & Science College, Shirur (K) Dist-Beed, Maharashtra, India Author
  • Shailendrasingh Thakur Department of Chemistry, Milliya College, Beed, Maharashtra, India Author

DOI:

https://doi.org/10.32628/IJSRST251396

Keywords:

pH metry, Gadolinium metal ion, medicinal drugs, Stability constants, Thermodynamic parameters

Abstract

We have used a pH metric titration technique in a 20% (v/v) ethanol-water mixture at three different temperatures at an ionic strength of 0.1M NaClO4 to measure the proton-ligand and metal-ligand stability constants of medicinal drugs containing Gadolinium metal ion (Gd3+). The logK values of the metal-ligand stability constant have been determined using the modified Irving-Rossotti and Calvin-Bjerrum method. The thermodynamic parameters Gibb's free energy change, entropy change and enthalpy change related to the complexation reactions were quantitatively determined.

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References

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Ramesh Ware, Kishore Koinkar,Ashish Katariya, Hansaraj Joshi, Shailendrasingh Thakur,(2024) “Formation of Copper metal complexes with medicinal drugs in ethanol warer media” International Journal of Scientific Research in Chemical Sciences,11(05),19-22.

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Published

12-08-2025

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Section

Research Articles

How to Cite

Complexation of Gadolinium Metal Ion with Medicinal Drugs in Mixed Solvent Media: Thermodynamic Aspect. (2025). International Journal of Scientific Research in Science and Technology, 12(4), 1107-1113. https://doi.org/10.32628/IJSRST251396