A Review on Mouth Dissolving Tablets
DOI:
https://doi.org/10.32628/IJSRST52411276Keywords:
Mouth Dissolving Tablet, Disintegration, Fast Dissolving, Traditional Dosage FormAbstract
Traditional dosage forms, such as pills and capsules, are now used to treat conditions like dysphagia, which increases the risk of non-compliance and makes therapy ineffective. Mouth dissolving tablets were created to solve the problems associated with traditional dosage forms. They offer good hardness, dose uniformity, and convenience of administration. For pediatric, geriatric, and travel patients, they are the preferred dose form. Providing the MDTs with enough hardness, integrity, and disintegration speed without the requirement for water was the aim of their development. For fast-dissolving tablets to dissolve in saliva quickly, water is not needed. Some tablets are designed to dissolve in saliva very quickly in just a few seconds and are therefore referred to as "fast-dissolving" tablets. Because they contain substances that accelerate the pace at which the tablet dissolves in the mouth otherwise, it might take up to a minute some tablets are best referred to as fast-disintegrating tablets. This tablet type is designed to make it possible to administer an oral solid dose form in situations when no water or fluids are taken. These tablets typically dissolve in less than 60 seconds when dissolved in saliva.
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Momin MM, Dev A. Fast dissolving tablets: a novel approach. Indian Journal of Pharmaceutical and Biological Research. 2015 Jan 1;3(1):18.
Jeong SH, Takaishi Y, Fu Y, Park K. Material properties for making fast dissolving tablets by a compression method. Journal of Materials Chemistry. 2008;18(30):3527-35.
McLaughlin R, Banbury S, Crowley K. Orally disintegrating tablets: the effect of recent FDA guidance on ODT technologies and applications.
Parkash V, Maan S, Yadav SK, Jogpal V. Fast disintegrating tablets: Opportunity in drug delivery system. Journal of advanced pharmaceutical technology & research. 2011 Oct;2(4):223.
Shukla D, Chakraborty S, Singh S, Mishra B. Mouth dissolving tablets I: An overview of formulation technology. Scientia Pharmaceutica. 2009 Jun;77(2):309-26.
Hirani JJ, Rathod DA, Vadalia KR. Orally disintegrating tablets: a review. Tropical journal of pharmaceutical research. 2009;8(2).
Patel BP, Patel JK, Rajput GC, Thakor RS. Formulation and evaluation of mouth dissolving tablets of cinnarizine. Indian journal of pharmaceutical sciences. 2010 Jul;72(4):522.
Fu Y, Yang S, Jeong SH, Kimura S, Park K. Orally fast disintegrating tablets: developments, technologies, taste-masking and clinical studies. Critical Reviews™ in Therapeutic Drug Carrier Systems. 2004;21(6).
Dollo G, Chevanne F, Le Corre P, Chemtob C, Le Verge R. Bioavailability of phloroglucinol in man. Journal de pharmacie de Belgique. 1999 May 1;54(3):75-82.
Gafiţanu E, Dumistrăcel I, Antochi S. Formulations and bioavailability of propyphenazone in lyophilized tablets. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi. 1991 Jan 1;95(1-2):127-8.
Chawla G, Jain N. Mouth dissolving tablets: an overview. International journal of pharmaceutical sciences and research. 2012 Sep 1;3(9):2919.
Joshi R, Garud N, Akram W. Fast dissolving tablets: a review. Int J Pharm Sci Res. 2020;11(4):1562-70.
Kumar S, Kaur H, Mishra PB, Vashisht N, Arora V. Mouth Dissolving Tablets: A Convenient Noval Dosage Form-A Review. International Journal of Pharmaceutical Research And Development. 2013;5(08):21-32.
Prateek S, Ramdayal G, Kumar SU, Ashwani C, Ashwini G, Mansi S. Fast dissolving tablets: a new venture in drug delivery. American Journal of PharmTech Research. 2012 Jul;2(4):252-79.
Sharma I, Sharma V. A comprehensive review on fast dissolving tablet technology. Journal of applied pharmaceutical science. 2011 Jul 30(Issue):50-8.
Bikshapathi D, Saikrishna K, KUMAR U, Sabitha G, Saikumar B. Fast dissolving tablets: an update. Int Res J Pharm. 2011;2(3):45-53.
Satpute MM, Tour NS. Formulation and in vitro evaluation of fast dissolving tablets of metoprolol tartrate. Brazilian Journal of pharmaceutical sciences. 2013;49:783-92.
Chandira RM, Venkataeswarlu BS, Kumudhavalli MV, Debjitbhowmik JB. Formulation and evaluation of mouth dissolving tablets of the etoricoxib. Pak. J. Pharm. Sci. 2010 Apr 1;23(2):178-81.
Puttewar TY, Kshirsagar MD, Chandewar AV, Chikhale RV. Formulation and evaluation of orodispersible tablet of taste masked doxylamine succinate using ion exchange resin. Journal of King Saud University-Science. 2010 Oct 1;22(4):229-40.
Harika K. Formulation and Evaluation of Oral Dispersible Tablet of Tramadol Hydrochloride (Doctoral dissertation, CL Baid Mehta College of Pharmacy, Chennai).
Mehta M, Bhagwat DP, Gupta GD. Fast dissolving tablets of sertraline hydrochloride. Int. J. Chem. Tech. Res. 2009 Oct;1(4):925-30.
Chacko AJ, Jose S, Babu N, Lucille MM. Design and development of orodispersible tablets of promethazine theoclate using coprocessed superdisintegrants and subliming materials. International Journal of Innovative Pharmaceutical Research. 2010;1(2):53-6.
Margret Chandira R, Venkataeswarlu B, Kumudhavalli M, Bhowmik D, Jayakar B. Formulation And Evaluation Of Mouth Dissolving Tablets Of The Etoricoxib.
Bagul U, Gujar K, Patel N, Aphale S, Dhat S. Formulation and evaluation of sublimed fast melt tablets of levocetirizine dihydrochloride. Int J Pharm Sci. 2010;2:76-80.
Hannan PA, Khan JA, Khan A, Safiullah S. Oral dispersible system: A new approach in drug delivery system. Indian journal of pharmaceutical sciences. 2016 Jan;78(1):2.
Roser BJ, Blair J, inventors; Quadrant Holdings Cambridge Ltd, assignee. Rapidly soluble oral solid dosage forms, methods of making same, and compositions thereof. United States patent US 5,762,961. 1998 Jun 9.
Allen LV, Wang B, Davies JD, inventors; University of Oklahoma, assignee. Method for producing a rapidly dissolving dosage form. United States patent US 6,066,337. 2000 May 23.
Shaikh NM, More TD. A REVIEW ON MOUTH DISSOLVING TABLET.
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