Development and Validation of UV-VIS Spectrophotometric Method for Determination of Triamcinolone from Dissolution Media

Suryawanshi P. S.; Kalshetti M. S.

doi:10.32628/IJSRST24113118

Authors

Suryawanshi P. S. D. S. T. S. Mandal’s College of Pharmacy, Solapur, Maharashtra, India Author
Kalshetti M. S. D. S. T. S. Mandal’s College of Pharmacy, Solapur, Maharashtra, India Author

DOI:

https://doi.org/10.32628/IJSRST24113118

Keywords:

Triamcinolone, Spectrophotometric, Development, Validation

Abstract

A simple, accurate UV-VIS Spectrophotometric method has been developed using a dissolution media, Tween 20 (0.15%) as a solvent to determine the Triamcinolone. At predetermined λmax of 240 nm, method was proved linear in the range of 10-50 µg/ml with good correlation coefficient (R2= 0.998) and excellent recovery (between 98 and 101%). This method was successfully applied to the determination of Triamcinolone from dissolution media, 0.15% Tween 20 aqueous solution. This method can be employed for the dissolution study of Triamcinolone in injectable suspension.

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References

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