Synthesis of Novel PCMX Derivative

Authors

  • Tanuja P. Parulekar Department of Chemistry, S.I.W.S. N.R. Swamy College of Commerce & Economics and Smt. Thirumalai College of Science, Wadala, Mumbai, Maharashtra, India Author
  • Vijay D. Gangan Department of Chemistry, Reena Mehta College of Arts, Commerce, Science and Management Studies, Bhayandar (W), Thane, Maharashtra, India Author

DOI:

https://doi.org/10.32628/IJSRST24114145

Keywords:

Para Chloro Meta Xylenol, Antibacterial, Antiseptic, Disinfectant, 1HNMR, Ester Molecule, Gram Positive, Gram Negative, Bacterial Cultures

Abstract

Chloroxylenol, or parachlorometaxylenol (PCMX), is an antiseptic and disinfectant agent used for skin disinfection and surgical instruments. It is found in antibacterial soaps, wound-cleansing applications, and household antiseptics. Their analogues viz. hybrid / ester molecules also possess various biological activities which prompted us to synthesize a novel analogue for their future application as bioactive molecule. The synthesized compound was unambiguously characterized by IR, 1HNMR, elemental analysis and mass spectral data.

Downloads

Download data is not yet available.

References

Wattenberg L. W., Coccia J. B.,Lam L. K. Inhibitory effects of phenolic compounds on benzo(a)pyrene-induced neoplasia. Cancer Res., 1980, 40, pp. 2820 – 2823.

Talalay P., De Long M. U., Prochaska H. J. Identification of a common chemical signal regulating the induction of enzymes that protects against chemical carcinogenesis. Proc. Natl. Acad. Sci. USA.

Macheix JJ., Fleuriet A.;Billot J. Fruit phenolics. Boca Raton, FL; CTC; 1990.

World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. p. 324. hdl:10665/44053. ISBN 9789241547659.

Griffiths, Christopher; Barker, Jonathan; Bleiker, Tanya; Chalmers, Robert; Creamer, Daniel (2016-02-29). Rook's Textbook of Dermatology, 4 Volume Set. John Wiley & Sons. p. 128.38. ISBN 9781118441176. Archived from the original on 2017-01-13.

Gangan V. D., Yadav U, Mewada K., Khandait S. A., Parulekar T. P., Singh A., Raddi K. Ester Derivatives of eugenol as potential Antibacterial agent. International journal of food and nutritional sciences, 2022, UGC Care listed Journal (Group I), Vol. 11 (10), pp. 2818 – 2825.

Parulekar T. P. and Gangan V. D. International Journal of Scientific Research in Science and Technology, 10 (6), November – December 2023, pp. 65 – 70.

Downloads

Published

04-09-2024

Issue

Section

Research Articles

How to Cite

Synthesis of Novel PCMX Derivative. (2024). International Journal of Scientific Research in Science and Technology, 11(5), 01-04. https://doi.org/10.32628/IJSRST24114145

Similar Articles

1-10 of 54

You may also start an advanced similarity search for this article.